These words refer to aversion or contempt towards anything one finds objectionable, distasteful or offensive.

Loathe is extensively used for simple distaste. It also focuses on aversion or dislike.

Ex – She loathed men who had mustaches or beards.

Despise usually indicates finding something offensive or morally objectionable.

Ex – He despised orthodox methods of punishing children.

Abhor is strongest among these words for suggesting outright hatred.

Ex – He abhorred men who had no moral principles.

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